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  2. COPD - What Is COPD? - NHLBI, NIH

    www.nhlbi.nih.gov/health/copd

    COPD Basics Learn who is at risk for COPD, what symptoms to watch for, and how the disease affects the lungs. COPD, or chronic obstructive pulmonary disease, is a condition caused by damage to the airways or other parts of the lung. This damage leads to inflammation and other problems that block airflow and make it hard to breathe.

  3. Model shows emphysema might be reversed with injection of healthy...

    www.nhlbi.nih.gov/news/2021/model-shows-emphysema-might-be...

    When the researchers deleted the gene for LRG1 from lung endothelial cells in mice, the animals’ lungs were largely protected from the lung damage of induced emphysema, much as they had been by the endothelial cell therapy. The study was funded by NHLBI.

  4. COPD - Alpha-1 Antitrypsin Deficiency - NHLBI, NIH

    www.nhlbi.nih.gov/health/alpha-1-antitrypsin-deficiency

    If you have emphysema and AAT, standard COPD treatments — bronchodilators, inhaled steroids, antibiotics, oral corticosteroids, regular vaccinations, pulmonary rehabilitation, oxygen therapy, and (for severe cases) surgery — may be given. If you have emphysema, you may need a lifelong treatment called augmentation therapy.

  5. COPD - Symptoms - NHLBI, NIH

    www.nhlbi.nih.gov/health/copd/symptoms

    For example, you may take the elevator instead of the stairs. For more serious symptoms, such as becoming short of breath during physical work, your healthcare provider can provide treatments and other ways to help. Severe COPD can cause additional symptoms, such as lack of appetite, loss of weight and muscle, anxiety, and depression.

  6. Bronchitis - Bronchitis - NHLBI, NIH

    www.nhlbi.nih.gov/health/bronchitis

    The symptoms are the same for both acute and chronic bronchitis: Cough with mucus; Chest pain; Tiredness; Low fever of below 100.4 degrees Fahrenheit; Shortness of breath; Wheezing; Symptoms of acute cases clear on their own after 2 − 3 weeks. With chronic bronchitis, a productive cough can last three months or longer.

  7. CHRONIC COUGH, SHORTNESS OF BREATH WHEEZING? - NHLBI, NIH

    www.nhlbi.nih.gov/sites/default/files/publications/Health...

    chronic bronchitis or emphysema. COPD, a leading cause of death, affects millions of Americans and causes long-term disability. Most often, COPD occurs in people age 40 and over who… • Have a history of smoking • Have had long-term exposure to lung irritants such as air pollution, chemical fumes, or dust from the environment or workplace

  8. Bronchodilators don’t improve smoking-related respiratory...

    www.nhlbi.nih.gov/news/2022/bronchodilators-dont-improve...

    In the 12-week, randomized, double-blinded study, which was part of the Redefining Therapy in Early COPD for the Pulmonary Trials Cooperative (RETHINC), researchers enrolled 535 adults with symptoms of COPD, ages 40-80, at one of 20 U.S. medical centers. Twice each day, study participants used an inhaler that contained either medication or a ...

  9. COPD - Causes and Risk Factors | NHLBI, NIH

    www.nhlbi.nih.gov/health/copd/causes

    Most people who have COPD are at least 40 years old when symptoms begin. A condition that runs in families, called alpha-1 antitrypsin (AAT) deficiency: If you are born with this condition, smoking or long-term exposure to fumes or dust can lead to lung damage and COPD. AAT deficiency can also raise your risk for developing COPD at a younger age.

  10. Pneumonia - Causes and Risk Factors | NHLBI, NIH

    www.nhlbi.nih.gov/health/pneumonia/causes

    Some bacteria cause pneumonia with different symptoms or other characteristics than the usual pneumonia. This infection is called atypical pneumonia. For example, Mycoplasma pneumoniae causes a mild form of pneumonia often called “walking pneumonia.” Legionella pneumophila causes a severe type of pneumonia called Legionnaires’ disease ...

  11. A Quick Guide on Chronic Obstructive Pulmonary Disease - NHLBI,...

    www.nhlbi.nih.gov/sites/default/files/publications/A-Quick...

    chronic bronchitis or emphysema. COPD, a leading cause of death, affects millions of Americans and causes long-term disability. Most often, COPD occurs in people age 40 and over who… • Have a history of smoking • Have had long-term exposure to lung irritants such as air pollution, chemical fumes, or dust from the environment or workplace