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Early artificial ligaments developed in the 1980s were ineffective due to material deterioration. [4] Currently, the Ligament Advanced Reinforcement System (LARS) artificial ligament has been utilized extensively in clinical applications. [5] Tissue engineering is a growing area of research which aims to regenerate and restore ligament function ...
When a high dose of prednisone cannot be reduced without losing muscle strength, or when prednisone is effective but it is producing significant complications, "steroid sparing" oral immunosuppressants such as azathioprine, mycophenolate mofetil, methotrexate and cyclosporine, may be used in combination with reduced prednisone. Some of these ...
Tendons and ligaments play an active role in maintaining joint stability and controls the limits of joint movements, once injured tendons and ligaments detrimentally impact motor functions. [ 2 ] [ 8 ] Continuous exercise or movement of a musculoskeletal injury can result in chronic inflammation with progression to permanent damage or disability.
In general, use a potent preparation short term and weaker preparation for maintenance between flare-ups. While there is no proven best benefit-to-risk ratio, [11] if prolonged use of a topical steroid on a skin surface is required, a pulse therapy should be undertaken.
The term was originally introduced to indicate a drug that reduces evidence of processes thought to underlie the disease, such as a raised erythrocyte sedimentation rate, reduced haemoglobin level, raised rheumatoid factor level, and more recently, a raised C-reactive protein level.
Davis's law is used in anatomy and physiology to describe how soft tissue models along imposed demands. It is similar to Wolff's law, which applies to osseous tissue.It is a physiological principle stating that soft tissue heal according to the manner in which they are mechanically stressed.
The Broström operation (or Broström-Gould technique) is a repair of ligaments on lateral ankle. It is designed to address ankle instability. More importantly, it is primarily used to repair the anterior talofibular ligament (ATFL) in the ankle. It is thought that the majority of patients regain most function in their ankles.
Ligament Advanced Reinforcement System (LARS) The anterior cruciate ligament (ACL) of the knee is commonly injured. There is insufficient re-vascularization of the ligament after complete rupture, which limits its ability to heal and necessitates reconstruction surgery. Within the last 20 years, new types of synthetic ligaments have been developed.