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The smallest device approved by the FDA, the HeartMate II, weighs about 1 pound (0.45 kg) and measures 3 inches (7.6 cm). This has proven particularly important for women and children, for whom alternatives would have been too large. [45] As of 2017, HeartMate III has been approved by the FDA.
With the 2001 Thermo Cardiosystems merger, Thoratec acquired the HeartMate Left Ventricular Assist System, an implanted VAD for end-stage heart patients. A landmark three-year study of 129 patients at 22 major medical centers, called REMATCH (Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure) and published in November 2001, found that the HeartMate VE ...
O. H. "Bud" Frazier is a heart surgeon and director of cardiovascular surgery research at the Texas Heart Institute (THI), best known for his work in mechanical circulatory support (MCS) of failing hearts using left ventricular assist devices (LVAD) and total artificial hearts (TAH).
[2] [3] In addition, destination therapy may in some cases turn out to remedy the condition that excluded transplantation [4] Estimates place the population in the United States that may benefit from destination therapy at 50,000 – 100,000 patients per year. The addressable population outside of the US is thought be similar in size.
The user guide engraved into a model of the Antikythera Mechanism. User guides have been found with ancient devices. One example is the Antikythera Mechanism, [1] a 2,000 year old Greek analogue computer that was found off the coast of the Greek island Antikythera in the year 1900.
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2007 Toyota Yaris hatchback owner's manual 1919 Ford Motor Company car and truck operating manual. An owner's manual (also called an instruction manual or a user guide) is an instructional book or booklet that is supplied with almost all technologically advanced consumer products such as vehicles, home appliances and computer peripherals.
This manual supersedes FM 3-0, dated 6 October 2017. James C. McConville: INACTIVE: ADP 3–0 (FM 3–0) ADP 3–0, Unified Land Operations: 10 October 2011 [13] This manual supersedes FM 3–0, dated 27 February 2008 and Change 1, dated 22 February 2011. Raymond T. Odierno: INACTIVE: FM 3–0 (incl. C1) FM 3–0, Operations (with included ...