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Neuroinflammation is inflammation of the nervous tissue. It may be initiated in response to a variety of cues, including infection, traumatic brain injury, [1] toxic metabolites, or autoimmunity. [2] In the central nervous system (CNS), including the brain and spinal cord, microglia are the resident innate immune cells that are activated in ...
Neuritis (/ njʊəˈraɪtɪs /), from the Greek νεῦρον), [1] is inflammation of a nerve [2] or the general inflammation of the peripheral nervous system. Inflammation, and frequently concomitant demyelination, [3][4][5] cause impaired transmission of neural signals and leads to aberrant nerve function. Neuritis is often conflated with ...
Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
A neurodegenerative disease is caused by the progressive loss of neurons, in the process known as neurodegeneration. [2][3] Neuronal damage may also ultimately result in their death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple ...
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly in the grey matter of the brain. [1][2][3][4] Degenerative neuronal elements and an abundance of microglia and astrocytes can be associated with amyloid plaques.
Neuromyelitis optica spectrum disorder. Neuromyelitis optica spectrum disorders (NMOSD) are a spectrum of autoimmune diseases characterized by acute inflammation of the optic nerve (optic neuritis, ON) and the spinal cord (myelitis). [1][2][3] Episodes of ON and myelitis can be simultaneous or successive.
Cracking your neck too hard or too often could lead to: Pinched nerve. Stroke. Blood clot. Osteoarthritis. While these are low risk, the risk is higher for individuals who have conditions such as ...
Inflammatory demyelinating diseases (IDDs), sometimes called Idiopathic (IIDDs) due to the unknown etiology of some of them, are a heterogenous group of demyelinating diseases - conditions that cause damage to myelin, the protective sheath of nerve fibers - that occur against the background of an acute or chronic inflammatory process.