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Urea in low doses is a humectant while at high doses (above 20%) it causes breakdown of protein in the skin. [ 9 ] Urea dissolves the intercellular matrix of the cells of the stratum corneum , promoting desquamation of scaly skin , eventually resulting in softening of hyperkeratotic areas. [ 5 ]
The structure of the molecule of urea is O=C(−NH 2) 2.The urea molecule is planar when in a solid crystal because of sp 2 hybridization of the N orbitals. [8] [9] It is non-planar with C 2 symmetry when in the gas phase [10] or in aqueous solution, [9] with C–N–H and H–N–H bond angles that are intermediate between the trigonal planar angle of 120° and the tetrahedral angle of 109.5°.
Sudocrem (/ ˈ s u d ə k r ɛ m / or / ˈ s u d ə k r i m / in Ireland) [3] is an over-the-counter medicated cream aimed primarily at the treatment of irritant diaper dermatitis.It contains a water-repellent base (consisting of oils/waxes); protective and moisturizer agents; antibiotic and antifungal agents; and a weak anesthetic.
Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]
Walgreens Boots Alliance, Inc. (WBA) is an American multinational holding company headquartered in Deerfield, Illinois. [2] The company was formed on December 31, 2014, after Walgreens bought the 55% stake in Alliance Boots (owner of Boots UK Limited ) that it did not already own.
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Ichthammol or ammonium bituminosulfonate (brand name Ichthyol), also known as black ointment, is a medication derived from sulfur-rich oil shale (bituminous schists). It is used (sometimes in combination with zinc oxide) as a treatment for different skin diseases, including eczema and psoriasis (see below).
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