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Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
High-dose estrogen therapy (HDE) is a type of hormone therapy in which high doses of estrogens are given. [1] When given in combination with a high dose of progestogen , it has been referred to as pseudopregnancy .
Gynecomastia (also spelled gynaecomastia) [a] is the non-cancerous enlargement of one or both breasts in men due to the growth of breast tissue as a result of a hormone imbalance between estrogens and androgens.
Treatment: A couple of options for treating menopause-related dryness are prescription local vaginal estrogen pills, creams, or rings. There are also non-hormonal options such as DHEA and the CO2 ...
In the past, it was used at even higher doses of 10 to 40 every 1 to 4 weeks for estrogen replacement. [36] Estradiol valerate is usually used in the treatment of advanced prostate cancer in men at a dosage of 30 mg or more every 1 to 2 weeks by intramuscular injection. [13]
It can manifest as precocious puberty, and is caused by abnormally high levels of testosterone or estrogen, crucial hormones for sexual development. In some cases, it may be caused by a tumor, which can be malignant, but is more commonly benign. [2] Anabolic steroids may also be a major cause of high androgen and estrogen functional activity.
Hone Health reports on the factors responsible for testosterone levels in men and how they are affected by age and lifestyle.