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Epidemics and pandemics with at least 1 million deaths Rank Epidemics/pandemics Disease Death toll Percentage of population lost Years Location 1 1918 Flu: Influenza A/H1N1: 17–100 million 1–5.4% of global population [4] 1918–1920 Worldwide 2 Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549
The term pandemic had not been used then, but was used for later epidemics, including the 1918 H1N1 influenza A pandemic—more commonly known as the Spanish flu—which is the deadliest pandemic in history. The most recent pandemics include the HIV/AIDS pandemic, the 2009 swine flu pandemic and the COVID-19 pandemic. Almost all these diseases ...
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
A pandemic (/ p æ n ˈ d ɛ m ɪ k / pan-DEM-ik) is an epidemic of an infectious disease that has a sudden increase in cases and spreads across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals.
Second-deadliest disaster in United States history. Deadliest drug epidemic in United States history. 700,000 [3] 1981 – present HIV/AIDS in the United States: Pandemic Nationwide Fatalities estimated. Third-deadliest disaster in United States history. 675,000 [4] 1918 – 1920 1918 influenza pandemic: Pandemic Nationwide Fatalities estimated.
COVID-19 is the deadliest pandemic in US history; [359] it was the third-leading cause of death in the US in 2020, behind heart disease and cancer. [360] From 2019 to 2020, US life expectancy dropped by 3 years for Hispanic Americans, 2.9 years for African Americans, and 1.2 years for white Americans. [361]
The 1918 flu pandemic, commonly referred to as the Spanish flu, was a category 5 influenza pandemic caused by an unusually severe and deadly Influenza A virus strain of subtype H1N1. The difference between the influenza mortality age-distributions of the 1918 epidemic and normal epidemics.
The Black Death was a bubonic plague pandemic that occurred in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3]