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The US Food and Drug Administration (FDA) approved spesolimab based on evidence from a clinical trial of 53 adults with generalized pustular psoriasis flare. [6] The trial was conducted at three sites in the United States and 23 sites globally (Africa, Asia, and Europe). [6]
Moderate to severe psoriasis with or without arthritis typically requires systemic treatment in the form of small molecule disease-modifying drugs, such as methotrexate and systemic retinoids or ...
The history of psoriasis is littered with treatments of dubious effectiveness and high toxicity. In the 18th and 19th centuries, Fowler's solution, which contains a poisonous and carcinogenic arsenic compound, was used by dermatologists as a treatment for psoriasis. [134] Mercury was also used for psoriasis treatment during this time. [134]
Psoriasis occurs when a person's immune system becomes overactive, leading to the rapid multiplication of their skin cells. This results in scaly, inflamed patches of skin, most likely on the ...
Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
The Good News About Psoriasis. THE FDA HAS approved 13 different “biologic” drugs—those that act on your immune system—for the treatment psoriasis so far. Yes, 13 is a lot, but a doc can ...
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