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Fluoride toothpaste prevents about 25% of cavities in young permanent teeth, and its effectiveness is improved if higher concentrations of fluoride are used, or if the toothbrushing is supervised. Fluoride mouthwash and gel are about as effective as fluoride toothpaste; fluoride varnish prevents about 45% of cavities. [93]
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
Fluorine is often added to drug molecules during drug design, as even a single atom can greatly change the chemical properties of the molecule in desirable ways. Because of the considerable stability of the carbon–fluorine bond , many drugs are fluorinated to delay their metabolism , which is the chemical process in which the drugs are turned ...
The widespread use of toothpaste and mouthwashes with added fluoride in recent decades appears to have diminished the health benefits of water fluoridation, according to a new study.
Water and food sources of fluoride include community water fluoridation, seafood, tea, and gelatin. [ 52 ] Soluble fluoride salts, of which sodium fluoride is the most common, are toxic, and have resulted in both accidental and self-inflicted deaths from acute poisoning . [ 4 ]
Evidence confirms that water fluoridation is a safe and effective way to help protect teeth against decay [12]: 4-5 The addition of fluoride to the water does not alter the taste or smell of the drinking water [citation needed] Fluoride therapy is often used to promote remineralization.
U.S. standards recommend fluoride levels of 0.7 milligrams per liter of water, and the NTP’s conclusion applied to water fluorinated at 1.5 milligrams per liter and above.
The American Association of Pediatrics also maintains that fluoride in drinking water and toothpaste is a safe means of boosting children's oral health. Charlotte W. Lewis, ...
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