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Human B1 cells have been found to have marker profile of CD20+CD27+CD43+CD70- and could either be CD5+ or CD5-, which has been debated since. [3] CD5-CD72 is thought to mediate B cell-B cell interaction. What differentiates B1 cells from other B cells is the variable existence of CD5, CD86, IgM and IgD. [1]
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. [1] They function in the humoral immunity component of the adaptive immune system. [1] B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors. [2]
1 B1 cell group. 2 B2 cell group. 3 B3 cell group. 4 B4 cell group. 5 B5 cell group. 6 B6 cell group. 7 B7 cell group. 8 B8 cell group. 9 B9 cell group. 10 References ...
Regulatory B cells (Bregs or B reg cells) represent a small population of B cells that participates in immunomodulation and in the suppression of immune responses. The population of Bregs can be further separated into different human or murine subsets such as B10 cells, marginal zone B cells, Br1 cells, GrB + B cells, CD9 + B cells, and even some plasmablasts or plasma cells.
Similar to B1 B cells, MZ B cells can be rapidly recruited into the early adaptive immune responses in a T cell-independent manner. [9] The MZ B cells are especially well-positioned as the first line of defense against systemic blood-borne antigens that enter the circulation and become trapped in the spleen. [10]
When reintroduced to antigen, some of these B1 cells can differentiate into memory B cells without interacting with a T cell. [4] These B cells produce IgM antibodies to help clear infection. [20] T-bet memory B cells. T-bet B cells are a subset that have been found to express the transcription factor T-bet. T-bet is associated with class ...
Transitional B cells are B cells at an intermediate stage in their development between bone marrow immature cells and mature B cells in the spleen.Primary B cell development takes place in the bone marrow, where immature B cells must generate a functional B cell receptor (BCR) and overcome negative selection induced by reactivity with autoantigens. [1]
Pages in category "Human cells" The following 137 pages are in this category, out of 137 total. ... B cell; B1 cell; Basophil; Basophil activation; Basophilia;