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Uterine clear cell tumors arise from an endometrium that has become thin and dry. [7] Patients usually present with abnormal uterine bleeding. Treatment of uterine clear cell carcinoma is primarily surgical. A tumor debulking procedure is typically performed, consisting of a total hysterectomy and bilateral salpingo-oopherectomy.
Debulking is the reduction of as much of the bulk of a tumour without the intention of a complete eradication. It is usually achieved by surgical removal. [1] [2] When performed for curative intent, it is a different procedure, which is called surgical debulking of tumors is known as cytoreduction or cytoreductive surgery [3] (CRS); "cytoreduction" refers to reducing the number of tumor cells.
Clear-cell carcinoma, also known as clear-cell adenocarcinoma and mesonephroma, [1] is an epithelial-cell-derived carcinoma characterized by the presence of clear cells observed during histological, diagnostic assessment. This form of cancer is classified as a rare cancer with an incidence of 4.8% in white patients, 3.1% in black patients, and ...
Carcinosarcoma of the uterus. In gross appearance, MMMTs are fleshier than adenocarcinomas, may be bulky and polypoid, and sometimes protrude through the cervical os.On histology, the tumors consist of adenocarcinoma (endometrioid, serous or clear cell) mixed with the malignant mesenchymal elements; alternatively, the tumor may contain two distinct and separate epithelial and mesenchymal ...
In 1944, Meigs repopularized the surgical approach when he developed a modified Wertheim operation with removal of all pelvic nodes. [ 2 ] [ 4 ] Meigs reported a survival rate of 75% for patients with stage I disease and demonstrated an operative mortality rate of 1% when these procedures were performed by a specially trained gynecologist.
Type 1 endometrial cancer is the most common endometrial cancer. [16] As many as 90% of patients diagnosed with Type 1 endometrial cancer are obese. [ 17 ] Although a correlation between obesity and ovarian cancer is possible, the association is predominantly found in low-grade subtypes of the cancer.
For endometrial cancer, five main types of treatments are used, including surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy. The most common treatment modality for endometrial cancer is surgery, whereby the uterus is removed via a total hysterectomy. [15]
Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. [1] The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they produce will fill the abdominal cavity.