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A caries vaccine is a vaccine to prevent and protect against tooth decay. [1] Streptococcus mutans ( S. mutans ) has been identified as the major etiological agent of human dental caries. The development of a vaccine for tooth decay has been under investigation since the 1970s.
Odontogenic sinusitis is an inflammatory condition of the paranasal sinuses that is the result of dental pathology, most often resulting from prior dentoalveolar procedures, infections of maxillary dentition, or maxillary dental trauma. [6] Infections associated with teeth may be responsible for approximately 20% of cases of maxillary sinusitis ...
Ecological plaque hypothesis and the aetiology of dental caries The ecological plaque hypothesis, a combination of the two previously mentioned hypotheses, suggests that there are certain species responsible for pathology, but are present in insufficient quantities to cause damage to a healthy individual. [ 13 ]
Dental caries result when the demineralization rate is faster than the remineralization, producing net mineral loss, which occurs when there is an ecologic shift within the dental biofilm from a balanced population of microorganisms to a population that produces acids and can survive in an acid environment.
The causative agent of dental caries is associated with its ability to metabolize various sugars, form a robust biofilm, produce an abundant amount of lactic acid, and thrive in the acid environment it generates. [19] A study into pH of plaque said that the critical pH for increased demineralisation of dental hard tissues (enamel and dentine ...
Dental caries (cavities), described as "tooth decay", is an infectious disease which damages the structures of teeth. [43] The disease can lead to pain , tooth loss , and infection. Dental caries has a long history, with evidence showing the disease was present in the Bronze , Iron , and Middle ages but also prior to the neolithic period. [ 44 ]
Representation of the progression of dental caries. Dental caries is an infectious disease caused primarily by Streptococcus mutans, characterized by acid demineralization of the enamel, which can progress to further breakdown of the more organic, inner dental tissue . [1]
Main building of Vipeholm hospital, now a secondary school. The Vipeholm experiments or Vipeholm Study (Swedish: Vipeholmsexperimenten) were a series of human experiments where patients of Vipeholm Hospital for the intellectually disabled in Lund, Sweden, were fed large amounts of sweets, including "extra sticky toffee" [clarification needed] to provoke dental caries.