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Neurogenic bowel dysfunction (NBD) is reduced ability or inability to control defecation due to deterioration of or injury to the nervous system, resulting in fecal incontinence or constipation. [1] It is common in people with spinal cord injury (SCI), multiple sclerosis (MS) or spina bifida .
Fecal impaction is a common result of neurogenic bowel dysfunction and causes immense discomfort and pain. Its treatment includes laxatives, enemas, and pulsed irrigation evacuation (PIE) as well as digital removal. It is not a condition that resolves without direct treatment.
neurons were strongly reduced all over the digestive tract; megacolon appeared only when there was a reduction of over 80% of the number of neurons these pathologies appeared as a result of the disruption of the neurally integrated control of peristalsis (muscular annular contraction) in those parts where a strong force is necessary to impel ...
Colon cancer could become the leading cause of cancer deaths in the U.S. for people ages 20-49 by the year 2040, according to experts. (Yahoo News Photo Staff) (Yahoo News Photo Staff)
Pancreatic cancer is the fifth most-common cause of cancer-related deaths in the United States, [8] and the seventh most-common in Europe. [9] In 2008, globally there were 280,000 new cases of pancreatic cancer reported and 265,000 deaths. [10] These cancers are classified as endocrine or nonendocrine tumors. The most common is ductal ...
One review stated that the most common causes of disruption to the defecation cycle are associated with pregnancy and childbirth, gynaecological descent, or neurogenic disturbances of the brain-bowel axis. [44] The pathophysiologic mechanisms are thought to be different in obstructed defecation compared with slow transit constipation. [43]
The distinction helps to narrow the possible causes and treatment. Common causes of small bowel obstruction include post-operative adhesions, hernias, intussusception, and intraabdominal tumors. Common causes of colonic obstruction include primary colon cancer, volvulus and post-operative adhesions. When the ileocecal valve is competent ...
Irritable bowel disease (IBD), which includes ulcerative colitis or Crohn’s disease, causes inflammation in the digestive tract, leading to a range of symptoms including pain, diarrhea, and less ...