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  2. Schwann cell - Wikipedia

    en.wikipedia.org/wiki/Schwann_cell

    The two types of Schwann cells are myelinating and nonmyelinating. [1] Myelinating Schwann cells wrap around axons of motor and sensory neurons to form the myelin sheath. The Schwann cell promoter is present in the downstream region of the human dystrophin gene that gives shortened transcript that are again synthesized in a tissue-specific manner.

  3. Myelinogenesis - Wikipedia

    en.wikipedia.org/wiki/Myelinogenesis

    Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.

  4. Neurilemma - Wikipedia

    en.wikipedia.org/wiki/Neurilemma

    Neurilemma (also known as neurolemma, sheath of Schwann, or Schwann's sheath) [1] is the outermost nucleated cytoplasmic layer of Schwann cells (also called neurilemmocytes) that surrounds the axon of the neuron. It forms the outermost layer of the nerve fiber in the peripheral nervous system. [2]

  5. Myelin - Wikipedia

    en.wikipedia.org/wiki/Myelin

    In the PNS, myelin protein zero (MPZ or P0) has a similar role to that of PLP in the CNS in that it is involved in holding together the multiple concentric layers of glial cell membrane that constitute the myelin sheath. The primary lipid of myelin is a glycolipid called galactocerebroside. The intertwining hydrocarbon chains of sphingomyelin ...

  6. Node of Ranvier - Wikipedia

    en.wikipedia.org/wiki/Node_of_Ranvier

    When a longitudinal section is made through a myelinating Schwann cell at the node, three distinctive segments are represented: the stereotypic internode, the paranodal region, and the node itself. In the internodal region, the Schwann cell has an outer collar of cytoplasm, a compact myelin sheath, and inner collar of cytoplasm, and the axolemma.

  7. Oligodendrocyte - Wikipedia

    en.wikipedia.org/wiki/Oligodendrocyte

    The myelin sheath is not continuous but is segmented along the axon's length at gaps known as the nodes of Ranvier. In the peripheral nervous system the myelination of axons is carried out by Schwann cells. [1] Oligodendrocytes are found exclusively in the CNS, which comprises the brain and spinal cord.

  8. Nerve tissue protein - Wikipedia

    en.wikipedia.org/wiki/Nerve_tissue_protein

    The first is oligodendrocyte, which can be found in the mammalian Central Nervous System (CNS). The second is Schwann cells, which are found in the Peripheral Nervous System (PNS). Myelination of axons by these Schwann cells are essential for normal nerve function. Peripheral nerves rely on communication between axons and Schwaan cells. [2]

  9. Myelin protein zero - Wikipedia

    en.wikipedia.org/wiki/Myelin_protein_zero

    Myelin protein zero is expressed by Schwann cells and accounts for over 50% of all proteins in the peripheral nervous system, making it the most common protein expressed in the PNS. [6] Mutations in myelin protein zero can cause myelin deficiency and are associated with neuropathies like Charcot–Marie–Tooth disease and Dejerine–Sottas ...