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Paraspinal inhibition is an osteopathic manipulative technique in which the fascia around the spine is softened with one's hands in order to decrease the sympathetic output from the sympathetic ganglion which reside in the paraspinal area.
The thoracolumbar fascia (lumbodorsal fascia or thoracodorsal fascia) is a complex, [1]: 1137 multilayer arrangement of fascial and aponeurotic layers forming a separation between the paraspinal muscles on one side, and the muscles of the posterior abdominal wall (quadratus lumborum, and psoas major [1]: 1137 ) on the other.
Ganglia within this chain are either cervical, thoracic, lumbar, or sacral. Preganglionic nerves from the spinal cord synapse at one of the chain ganglia, and the postganglionic fiber extends to an effector, a visceral organ in the thoracic cavity , abdominal cavity , or pelvic cavity .
Activation of trigger points may be caused by a number of factors, including acute or chronic muscle overload, activation by other trigger points (key/satellite, primary/secondary), disease, psychological distress (via systemic inflammation), homeostatic imbalances, direct trauma to the region, collision trauma (such as a car crash which stresses many muscles and causes instant trigger points ...
For example, a tumor in the chest area may cause breathing difficulty, chest pain, and trachea compression. If the tumor is located lower in the abdomen, it may cause abdominal pain and bloating . A tumor near the spinal cord may cause spinal deformity or spinal compression, leading to pain and loss of muscle control or sensation in the legs ...
An ongoing Phase 2 trial in 2016 presented data [164] showing that after 90 days, 2 out of 4 subjects had already improved two motor levels and had thus already achieved its endpoint of 2/5 patients improving two levels within 6–12 months. Six-month data was expected in January 2017. [165]
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3] [4] [5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6]
Moderate to severe spinal stenosis at the levels of L3/4 and L4/5 [further explanation needed] The diagnosis of spinal stenosis involves a complete evaluation of the spine. The process usually begins with a medical history and physical examination. X-ray and MRI scans are typically used to determine the extent and location of the nerve compression.