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Multicellular eukaryotes are made of two fundamental cell types: germ and somatic cells. Germ cells produce gametes and are the only cells that can undergo meiosis as well as mitosis. Somatic cells are all the other cells that form the building blocks of the body and they only divide by mitosis. The lineage of germ cells is called the germline.
Parietal epithelial cell (PEC) Podocyte; Angioblast → Endothelial cell; Mesangial cell. Intraglomerular; Extraglomerular; Juxtaglomerular cell; Macula densa cell; Stromal cell → Interstitial cell → Telocytes; Kidney proximal tubule brush border cell; Kidney distal tubule cell; Connecting tubule cells; α-intercalated cell; β-intercalated ...
A germ layer is a primary layer of cells that forms during embryonic development. [1] The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans (animals that are sister taxa to the sponges) produce two or three primary germ layers.
Metagenomic analyses recover a two-domain system with the domains Archaea and Bacteria; in this view of the tree of life, Eukaryotes are derived from Archaea. [ 58 ] [ 59 ] [ 60 ] With the later gene pool of LUCA's descendants, sharing a common framework of the AT/GC rule and the standard twenty amino acids, horizontal gene transfer would have ...
In addition, stem cell are undifferentiated cells which can develop into a specialized cell and are the earliest type of cell in a cell lineage. [2] Due to the differentiation in function, somatic cells are found only in multicellular organisms, as in unicellular ones the purposes of somatic and germ cells are consolidated in one cell.
The mutation frequencies for cells in different stages of gametogenesis are about 5 to 10-fold lower than in somatic cells both for spermatogenesis [18] and oogenesis. [19] The lower frequencies of mutation in germline cells compared to somatic cells appears to be due to more efficient DNA repair of DNA damages, particularly homologous ...
The eukaryotic cell seems to have evolved from a symbiotic community of prokaryotic cells. DNA-bearing organelles like mitochondria and chloroplasts are remnants of ancient symbiotic oxygen-breathing bacteria and cyanobacteria, respectively, where at least part of the rest of the cell may have been derived from an ancestral archaean prokaryote ...
PGC-like cells generated using this method can be transplanted into a gonad, where the differentiate, and are able to give viable gametes and offspring in vivo. [34] PGC-like cells can also be generated from naïve embryonic stem cells (ESCs) that are cultured for two days in the presence of FGF and Activin-A to adopt an epiblast-like state.