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This is an accepted version of this page This is the latest accepted revision, reviewed on 2 February 2025. Computer program that modifies other programs to replicate itself and spread Hex dump of the Brain virus, generally regarded as the first computer virus for the IBM Personal Computer (IBM PC) and compatibles A computer virus is a type of malware that, when executed, replicates itself by ...
Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]
To enter the cells, proteins on the surface of the virus interact with proteins of the cell. Attachment, or adsorption, occurs between the viral particle and the host cell membrane. A hole forms in the cell membrane, then the virus particle or its genetic contents are released into the host cell, where replication of the viral genome may commence.
Virus classification is the process of naming viruses and placing them into a taxonomic system similar to the classification systems used for cellular organisms.
Double-stranded RNA viruses (dsRNA viruses) are a polyphyletic group of viruses that have double-stranded genomes made of ribonucleic acid.The double-stranded genome is used as a template by the viral RNA-dependent RNA polymerase (RdRp) to transcribe a positive-strand RNA functioning as messenger RNA (mRNA) for the host cell's ribosomes, which translate it into viral proteins.
The term is variously used to refer to viral particles shedding from a single cell, from one part of the body into another, [2] and from a body into the environment, where the virus may infect another. [3] Vaccine shedding is a form of viral shedding which can occur in instances of infection caused by some attenuated (or "live virus") vaccines.
An RNA virus is a virus characterized by a ribonucleic acid based genome. [1] The genome can be single-stranded RNA ( ssRNA ) or double-stranded ( dsRNA ). [ 2 ] Notable human diseases caused by RNA viruses include influenza , SARS , MERS , COVID-19 , Dengue virus , hepatitis C , hepatitis E , West Nile fever , Ebola virus disease , rabies ...
Adeno Associated Virus (AAV) (lower panel) – To produce AAV, package a gene of interest into the AAV-ITR vector and transfect cells with a Helper vector and the Rep/Cap DNA integration vector. Adeno-associated viruses (AAVs) are relatively small single-stranded DNA viruses belonging to Parvoviridae and, like lentiviral vectors, AAVs can ...