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The COPII coat consists of an inner layer – a flexible meshwork of Sar1, Sec23, and Sec24 – and an outer layer made of Sec13 and Sec31. [1] Sar1 resembles other Ras-family GTPases, with a core of six beta strands flanked by three alpha helices , and two flexible "switch domains".
Stibitz was born in York, Pennsylvania, the son of Mildred Murphy, a math teacher, and George Stibitz, a German Reformed minister and theology professor. Throughout his childhood, Stibitz enjoyed assembling devices and systems, working with material as diverse as a toy Meccano set or the electrical wiring of the family home. [3]