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During intensive prolonged endurance or strength training, the body signals the heart to pump more blood through the body to counteract the oxygen deficit building in the skeletal muscles. Enlargement of the heart is a natural physical adaptation of the body to deal with the high pressures and large amounts of blood that can affect the heart ...
The effects of high altitude on humans are mostly the consequences of reduced partial pressure of oxygen in the atmosphere. The medical problems that are direct consequence of high altitude are caused by the low inspired partial pressure of oxygen, which is caused by the reduced atmospheric pressure, and the constant gas fraction of oxygen in ...
Increased oxygen consumption during sustained exercise reduces the oxygen saturation of venous blood, which can reach less than 15% in a trained athlete; although breathing rate and blood flow increase to compensate, oxygen saturation in arterial blood can drop to 95% or less under these conditions. [28]
Cardiovascular fitness measures how well the heart and blood vessels can transport oxygen to the muscles during exercise. It is an important component of overall fitness and has been linked to numerous health benefits, including a reduced risk of cardiovascular disease, improved cognitive function, and increased longevity.
Normal arterial blood oxygen saturation levels in humans are 96–100 percent. [1] If the level is below 90 percent, it is considered low and called hypoxemia . [ 2 ] Arterial blood oxygen levels below 80 percent may compromise organ function, such as the brain and heart, and should be promptly addressed.
Hypoxemia is usually defined in terms of reduced partial pressure of oxygen (mm Hg) in arterial blood, but also in terms of reduced content of oxygen (ml oxygen per dl blood) or percentage saturation of hemoglobin (the oxygen-binding protein within red blood cells) with oxygen, which is either found singly or in combination. [2] [5]
Venous blood with an oxygen concentration of 15 mL/100 mL would therefore lead to typical values of the a-vO 2 diff at rest of around 5 mL/100 mL. During intense exercise, however, the a-vO 2 diff can increase to as much as 16 mL/100 mL due to the working muscles extracting far more oxygen from the blood than they do at rest. [citation needed]
Heart rate, ventilatory rate, and ventilatory exchange of oxygen and carbon dioxide can indicate exercise intensity, but each of these can be confounded by effects independent of exercise intensity, and they are probably also mainly proxies for perfusion. Even if the data could be easily collected, it is not known how it would be usefully used.
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