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Urolithins are microflora metabolites of dietary ellagic acid derivatives, such as ellagitannins. [1] They are produced in the gut , and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing foods, such as pomegranate . [ 2 ]
When synthesized and absorbed in the intestines, urolithin A enters the systemic circulation where it becomes available to tissues throughout the body where it is further subjected to additional chemical transformations (including glucuronidation, methylation, sulfation, or a combination of them) within the enterocytes and hepatocytes. [9]
Urolithin B (UB) [1] is an urolithin, a type of phenolic compounds produced in the human gut after absorption of ellagitannins-containing food such as pomegranate, [2] strawberries, red raspberries, walnuts or oak-aged red wine. [3] Urolithin B is found in the urine in the form of urolithin B glucuronide. [citation needed]
The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra.The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, control levels of electrolytes and metabolites, and regulate blood pH.
The intercalated A cells are stimulated when the body is experiencing acidic conditions. Under acidic conditions, the high concentration of CO 2 in the blood creates a gradient for CO 2 to move into the cell and push the reaction HCO 3 + H ↔ H 2 CO 3 ↔ CO 2 + H 2 O to the left.
When anatomists refer to the right and left of the body, it is in reference to the right and left of the subject, not the right and left of the observer. When observing a body in the anatomical position, the left of the body is on the observer's right, and vice versa. These standardized terms avoid confusion. Examples of terms include: [2]: 4