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Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma, [9] [11] but discontinued for use in triple-negative breast cancer (TNBC). [12]
The subcutaneous injection of atezolizumab and hyaluronidase was evaluated in IMscin001 (NCT03735121), an open-label, multi-center, international, randomized trial in adults with locally advanced or metastatic non-small cell lung cancer who were not previously exposed to cancer immunotherapy and who had disease progression following treatment with platinum-based chemotherapy. [2]
The study enrolled 34 patients, 28 of which underwent surgery to resect the PDAC. 19 of the patients who had undergone surgery then received atezolizumab, an immune checkpoint inhibitor. 16 of the patients on atezolizumab then received autogene cevumeran. 1 patient was considered to have insufficiently many neoantigens to manufacture the vaccine.
Atezolizumab (Tecentriq) is a fully humanised IgG1 (immunoglobulin 1) antibody developed by Roche Genentech. In 2016, the FDA approved atezolizumab for urothelial carcinoma and non-small cell lung cancer. Avelumab (Bavencio) is a fully human IgG1 antibody developed by Merck Serono and Pfizer.
Bang Bang's current logo. This is a list of television programs currently broadcast (in first-run or reruns), scheduled to be broadcast, or formerly broadcast on Bang Bang, an Albanian television channel by DigitAlb that airs a mix of animated television series, animated and live-action films as well as live-action Albanian originals produced by DigitAlb.
The Academy of Sciences of Albania (Albanian: Akademia e Shkencave e Shqipërisë), founded in 1972, is the most important scientific institution in Albania. [1] In the 1980s, several research institutes began at the University of Tirana were transferred to the Academy's jurisdiction. [ 2 ]
Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Atezolizumab. PubMed provides review articles from the past five years (limit to free review articles)
Welcome to the Wayne (Miresevini ne Uejn) [190] Wide-Eye (Buf symadhi) [191] Wishenpoof! (Prekje magjike) [192] Waybuloo (Urra) Wonder Pets! (Kafshët fantastike)