Search results
Results from the WOW.Com Content Network
It was known by the developmental code name CI-581. [19] After promising preclinical research in animals, ketamine was tested in human prisoners in 1964. [31] These investigations demonstrated ketamine's short duration of action and reduced behavioral toxicity made it a favorable choice over phencyclidine (PCP) as an anesthetic. [141]
Currently, the lack of large, replicated clinical trials prevent existing results from being generalisable to the larger population. The current model of KAP also uses repeated administration of ketamine, the long-term side effects of which are not fully known yet. High doses of ketamine could also have potentially toxic effects in patients. [27]
Common side effects include numbness, feeling tired, nausea, diarrhea, and low blood cell counts. [5] [6] Other serious side effects include allergic reactions. [6] [5] Use in pregnancy is known to harm the baby. [5] Oxaliplatin is in the platinum-based antineoplastic family of medications. [7] It is believed to work by blocking the duplication ...
The finding by the Los Angeles County medical examiner that "Friends" star Matthew Perry died from "acute effects" of ketamine is generating interest in the drug.. Ketamine is generally safe when ...
Matthew Perry’s death has been ruled an accident from the “acute effects of ketamine,” officials in Los Angeles have confirmed. A summary of the post-mortem examination from the County of ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.
Ketamir-2 is under investigation for its potential to treat neurological and neuro MIRA Pharmaceuticals is developing the next generation of oral ketamine and pharmaceutical marijuana analogs to ...