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In the mouse gonadal primordium, the genital ridge, which forms from intermediate mesoderm, becomes morphologically distinct at E10.5. By E12, sexual differentiation of the gonad is apparent, indicating that genes involved in the formation of the bipotential gonad are expressed before E10.5 and E12.
During this time, primordial germ cells migrate from the yolk sac to the genital ridge; a region of mesenchyme arising from, and running parallel with, the mesonephros. The paramesonephric ducts are formed by the craniocaudal invagination of a ribbon of thickened coelomic epithelium that extends from the third thoracic segment caudally to the ...
In the female, the paramesonephric ducts persist and undergo further development. The portions which lie in the genital cord [citation needed] fuse to form the uterus and vagina. This fusion of the paramesonephric ducts begins in the third month, and the septum formed by their fused medial walls disappears from below upward.
A primordium (/ p r aɪ ˈ m ɔːr d i ə m /; pl.: primordia; synonym: anlage) in embryology, is an organ or tissue in its earliest recognizable stage of development. [1] Cells of the primordium are called primordial cells .
The reproductive system begins development at four to five weeks of gestation with germ cell migration. The bipotential gonad results from the collection of the medioventral region of the urogenital ridge. At the five-week point, the developing gonads break away from the adrenal primordium. Gonadal differentiation begins 42 days following ...
The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals.
From ancient history to the modern day, the clitoris has been discredited, dismissed and deleted -- and women's pleasure has often been left out of the conversation entirely. Now, an underground art movement led by artist Sophia Wallace is emerging across the globe to challenge the lies, question the myths and rewrite the rules around sex and the female body.
As development proceeds, the intermediate mesoderm differentiates sequentially along the anterior-posterior axis into three successive stages of the early mammalian and avian urogenital system, named pronephros, mesonephros and metanephros respectively (anamniote embryos form only a pronephros and mesonephros). [2]