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Apocynum cannabinum. Apocynum cannabinum (dogbane, amy root, hemp dogbane, prairie dogbane, Indian hemp, rheumatism root, or wild cotton) [4] is a perennial herbaceous plant that grows throughout much of North America —in the southern half of Canada and throughout the United States. It is poisonous to humans, dogs, cats, and horses.
Over 2020–23, the FDA updated its safety concerns about CBD, [53] acknowledging the unknown effects of protracted use, how it affects the developing brain, fetus, or infants during breastfeeding, whether it interacts with dietary supplements or prescription drugs, whether male fertility is affected, and its possible side effects, such as ...
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Estriol is used in menopausal hormone therapy to treat menopausal symptoms, such as hot flashes, vulvovaginal atrophy, and dyspareunia (difficult or painful sexual intercourse). [12][4][13][26][18] The benefits of estriol on bone mineral density and osteoporosis prevention have been inconsistent and are less clear. [18][12] Estriol has been ...
Bladder symptoms affect women of all ages. However, bladder problems are most prevalent among older women. [79] Women over the age of 60 years are twice as likely as men to experience incontinence; one in three women over the age of 60 years are estimated to have bladder control problems. [73]
Frequency. ~40% of elderly adults, increasing with age. Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. [2] The frequent need to urinate may occur during the day, at night, or both. [4] Loss of bladder control (urge incontinence) may ...
Pelvic floor dysfunction is defined as a herniation of the pelvic organs through the pelvic organ walls and pelvic floor. The condition is widespread, affecting up to 50 percent of women at some point in their lifetime. [10] About 11 percent of women will undergo surgery for urinary incontinence or pelvic organ prolapse by age 80. [11]
In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index , [ 21 ] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation.