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JWH-338 [14] Dibenzopyran >10000: 111 ± 16: CB 2 (>90x) JWH-339 [14] Dibenzopyran >10000: 2317 ± 93: CB 2 (>4.3x) JWH-340 [14] Dibenzopyran: 135 ± 6: 30 ± 1: CB 2 (4.5x) JWH-341 [14] Dibenzopyran: 100 ± 8: 10 ± 0.1: CB 2 (10x) JWH-346 [13] Naphthoylpyrrole: 67 ± 6: 39 ± 2: CB 2 (1.72x) JWH-347 [13] Naphthoylpyrrole: 333 ± 17: 169 ± 17 ...
JWH-030 is a research chemical which is a cannabinoid receptor agonist. [2] It has analgesic effects and is used in scientific research. [ 3 ] It is a partial agonist at CB 1 receptors , with a K i of 87 nM, making it roughly half the potency of THC . [ 4 ]
JWH-150 ((1-butyl-5-phenylpyrrol-3-yl)-naphthalen-1-ylmethanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB 1 (K i = 60 ± 1nM) and CB 2 (K i = 15 ± 2nM) receptors, with a moderate four-fold selectivity for the CB 2 receptor.
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
JWH may refer to: John Wesley Hardin, an American gun-fighter from the 18th century; John W. Henry, futures trader and owner of the Boston Red Sox; John Winston Howard, former Prime Minister of Australia; JWH-133, a medication used to prevent Alzheimer's disease; John W. Huffman, creator of the JWH cannabinoids
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a full agonist [3] at both the CB 1 and CB 2 cannabinoid receptors. It is somewhat selective for the CB 1 subtype, with affinity at this subtype approximately 5× the affinity at CB 2 . [ 4 ]
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