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Some publications use a simpler form of this equation that doesn't correct for the reference range of free T4. It is calculated with T T S I = 100 ⋅ T S H ⋅ F T 4 {\displaystyle TTSI={100\cdot TSH\cdot FT4}} .
Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
Jostel's TSH index can be calculated with = + from equilibrium serum concentrations of thyrotropin (TSH), free T4 (FT4) and a correction coefficient derived from the logarithmic standard model (β = 0.1345).
The therapeutic target range TSH level for patients on treatment ranges between 0.3 and 3.0 μIU/mL. [18] For hypothyroid patients on thyroxine, measurement of TSH alone is generally considered sufficient. An increase in TSH above the normal range indicates under-replacement or poor compliance with therapy.
English: Reference ranges for thyroid's secretory capacity (SPINA-GT) and Jostel's TSH index (TSHI or JTI) compared to univariable reference ranges for thyrotropin (TSH) and free thyroxine (FT4), shown in the two-dimensional phase plane defined by serum concentrations of TSH and FT4.
The first-trimester normal range is below 2.5 mIU/L and the second and third trimesters normal range is below 3.0 mIU/L. [16] [44] Treatment should be guided by total (rather than free) thyroxine or by the free T 4 index. Similarly to TSH, the thyroxine results should be interpreted according to the appropriate reference range for that stage of ...
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When circulating in the body, T3 and T4 are bound to transport proteins. Only a small fraction of the circulating thyroid hormones are unbound or free, and thus biologically active. T3 and T4 levels can thus be measured as free T3 and T4, or total T3 and T4, which takes into consideration the free hormones in addition to the protein-bound hormones.
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