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In stage 3, anemia (reduced hemoglobin levels) is present but red blood cell appearance remains normal. [4] Changes in the appearance of red blood cells are the hallmark of stage 4; first microcytosis and then hypochromia develop. [4] Iron deficiency begins to affect tissues in stage 5, manifesting as symptoms and signs. [4]
Iron-deficiency anemia is anemia caused by a lack of iron. [3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [1]
Anemia is typically diagnosed on a complete blood count. Apart from reporting the number of red blood cells and the hemoglobin level, the automatic counters also measure the size of the red blood cells by flow cytometry , which is an important tool in distinguishing between the causes of anemia.
Iron deficiency, or sideropenia, is the state in which a body lacks enough iron to supply its needs. Iron is present in all cells in the human body and has several vital functions, such as carrying oxygen to the tissues from the lungs as a key component of the hemoglobin protein, acting as a transport medium for electrons within the cells in the form of cytochromes, and facilitating oxygen ...
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
When suspected, diagnosis is made by blood tests initially a complete blood count, and occasionally, bone marrow tests. [6] Blood tests may show fewer but larger red blood cells, low numbers of young red blood cells, low levels of vitamin B 12, and antibodies to intrinsic factor. [6] Diagnosis is not always straightforward and can be ...
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