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Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine . [ 4 ]
The thiazide drug class was discovered and developed at Merck and Co. in the 1950s. [3] The first approved drug of this class, chlorothiazide, was marketed under the trade name Diuril beginning in 1958. [3] In most countries, thiazides are the least expensive antihypertensive drugs available. [4]
Thiazide-type diuretics such as hydrochlorothiazide act on the distal convoluted tubule and inhibit the sodium-chloride symporter leading to a retention of water in the urine, as water normally follows penetrating solutes. Frequent urination is due to the increased loss of water that has not been retained from the body as a result of a ...
Losartan/hydrochlorothiazide, sold under the brand name Hyzaar among others, is a fixed-dose combination medication used to treat high blood pressure when losartan is not sufficient. [ 1 ] [ 2 ] It consists of losartan, an angiotensin II receptor blocker ; and hydrochlorothiazide , a thiazide diuretic .
It is a combination of telmisartan an angiotensin II receptor antagonist with hydrochlorothiazide a diuretic. [2] It may be used if telmisartan by itself is not sufficient. [5] It is taken by mouth. [5] Common side effects include dizziness, upper respiratory tract infections, nausea, diarrhea, and tiredness. [2]
Ozempic was approved by the FDA (U.S. Food and Drug Administration) in 2017 for type 2 diabetes and heart disease and is sometimes used off-label for weight management.
Metformin is a prescription medication used to treat high blood sugar in those with type 2 diabetes who are resistant to the effects of insulin. It’s in a class of drugs known as biguanides.
But because daily-use Cialis is prescribed at a lower dosage, some side effects appear less common and are generally less severe. For instance, in clinical trials, 11 to 15 percent of men reported ...