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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Because of its antiandrogenic activity, spironolactone can cause breast tenderness, gynecomastia (breast development), feminization in general, and demasculinization, as well as sexual dysfunction including loss of libido and erectile dysfunction, although these side effects are usually confined to high doses of spironolactone. [109]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

  4. Medication overuse headache - Wikipedia

    en.wikipedia.org/wiki/Medication_overuse_headache

    Common over-the-counter medicines that can cause headaches when overused include Excedrin Migraine, Cafergot, and Advil. [11] [12] Dietary and medicinal caffeine consumption appears to be a modest risk factor for chronic daily headache onset, regardless of headache type. [13] [14] A lifelong history of headaches is a major risk factor for MOH. [15]

  5. Headache attributed to a substance or its withdrawal - Wikipedia

    en.wikipedia.org/wiki/Headache_attributed_to_a...

    Headaches can be attributed to many different substances. Some of these include alcohol, NO, carbon monoxide poisoning, cocaine, caffeine and monosodium glutamate. Chronic use of certain medications used to treat headaches can also start causing headaches, known as medication overuse headaches. Headaches may also be a symptom of medication ...

  6. These 11 foods can cause headaches. How to find your ... - AOL

    www.aol.com/news/11-foods-cause-headaches...

    Migraines are the No. 1 cause of disability among young women, studies have found. Cohen also sees patients with other types of headaches — cluster, tension, and those that involve the face and ...

  7. Could Spironolactone Help Women With Hair Thinning, Facial ...

    www.aol.com/could-spironolactone-help-women-hair...

    When you start losing hair, Google quickly becomes your trusted advisor as you head toward Spiral City. This can be overwhelming, from looking up hair loss treatments to scouring social media.

  8. RALES (trial) - Wikipedia

    en.wikipedia.org/wiki/RALES_(trial)

    The trial was stopped early because the beneficial effect of spironolactone on all-cause death exceeded the prespecified discontinuation requirements. Spironolactone reduced the risk of death by 30% compared to placebo. Additionally, there was a 35% reduction in the risk of hospitalization for worsening heart failure in the spironolactone group.

  9. Everything I Wish I Knew About Taking Spironolactone for Acne

    www.aol.com/news/everything-know-taking...

    Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...

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