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Women with folate deficiency who become pregnant are more likely to give birth to low birth weight premature infants, and infants with neural tube defects and even spina bifida. In infants and children, folate deficiency can lead to failure to thrive or slow growth rate, diarrhea , oral ulcers , megaloblastic anemia , neurological deterioration .
Folic acid helps the body produce healthy red blood cells and new cells. ... Bread and flour will be fortified with an essential vitamin in a bid to prevent serious birth defects in hundreds of ...
Cobalamin (vitamin B 12) deficiency may lead to folate deficiency, which, in turn, increases homocysteine levels and may result in the development of cardiovascular disease or birth defects. [ 119 ] Sources
Risk factors include folate deficiency, ... Birth defect is a widely used term for a congenital malformation, ... Folic acid, or vitamin B 9, aids ...
Folic acid is to be added to non-wholemeal wheat flour in the UK to help prevent birth defects. Adding folic acid to flour could prevent around 200 cases of neural tube defects, such as spina ...
It is estimated current proposals will help prevent around 200 neural tube defects each year – around 20% of the annual UK total. Calls to increase folic acid levels in flour ‘to prevent more ...
A deficiency of folate itself does not cause neural tube defects. The association seen between reduced neural tube defects and folic acid supplementation is due to a gene-environment interaction such as vulnerability caused by the C677T methylenetetrahydrofolate reductase (MTHFR) variant.
Folic acid, which is the synthetic form of the vitamin folate, is critical both in pre- and peri-conception. [7] Deficiencies in folic acid may cause neural tube defects (NTDs). Women who had 0.4 mg of folic acid in their systems due to supplementing 3 months before childbirth significantly reduced the risk of NTDs. [29]