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Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. [10] It typically begins with a fever and feeling generally unwell . [ 10 ] This is followed a day or two later by flat discolored spots or bumps that may blister, on the hands, feet and mouth and occasionally buttocks and groin.
Enterovirus 71 (EV71), also known as Enterovirus A71 (EV-A71), is a virus of the genus Enterovirus in the Picornaviridae family, [1] notable for its role in causing epidemics of severe neurological disease and hand, foot, and mouth disease in children. [2] It was first isolated and characterized from cases of neurological disease in California ...
The incubation period for FMD virus has a range between one and 12 days. [12] [13] The disease is characterized by high fever that declines rapidly after two to three days, blisters inside the mouth that lead to excessive secretion of stringy or foamy saliva and to drooling, and blisters on the feet that may rupture and cause lameness.
The disease begins with flu-like symptoms, like fever and a sore throat, but after a few days the blisters appear. Horrible, itchy red spots can appear on your hands, feet and mouth -- and ...
Coxsackie A virus is a subgroup of enterovirus A, which are small, non-enveloped, positive-sense, single-stranded RNA viruses. Its protective, icosahedral capsid has an external portion that contains sixty copies of viral proteins (VP1,-2,-3) and an internal portion surrounding the RNA genome containing sixty copies of VP4 viral proteins.
The 1997 Sarawak HFMD outbreak is a hand, foot, and mouth disease (HFMD) outbreak from April until June caused by the Enterovirus 71 (EV-71) affecting 600 children in the state of Sarawak in Malaysia. [1] [2] Sarawak is the first state in Malaysia that reported HFMD outbreak. An estimated 28 to 31 of the infected children died as a result.
[6] [7] Since then, recurrent cyclical epidemics of HFMD have occurred in the country every two to three years. [6] While the root cause behind the recurrence of the disease remains a mystery, another factor that has been identified as increasing the spread of the disease among children is travel to neighbouring countries with high infection ...
The United Kingdom was affected in 1967 by an outbreak of foot-and-mouth disease.The outbreak was limited to an area on the Welsh border with Shropshire.The subsequent 2001 United Kingdom foot-and-mouth crisis spread more broadly and caused a national crisis for British agriculture and tourism. [1]