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Micrograph of a vacuolar interface dermatitis with dermal mucin, as may be seen in lupus. H&E stain. Vacuolar interface dermatitis (VAC, also known as liquefaction degeneration, vacuolar alteration or hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermal junction, with lymphocytic inflammation at the epidermis and ...
What it looks like: Like seborrheic dermatitis, perioral dermatitis causes red, inflamed skin and small pustules around the nose and mouth. Other symptoms to note : Flare-ups can be itchy and ...
Contact Dermatitis. Contact dermatitis is when a dry, red, scaly rash that can also look like fluid-filled blisters or poison ivy appears from coming in contact with an irritant or allergen, says ...
Causes of vacuolar interface dermatitis ; Main conditions [1] Characteristics Micrograph Photograph Generally/Not otherwise specified Typical findings, called "vacuolar interface dermatitis": [1] Mild inflammatory cell infiltrate along the dermoepidermal junction (black arrow in image) Vacuolization within the basal keratinocytes (white arrow ...
Dermatitis was estimated to affect 245 million people globally in 2015, [6] or 3.34% of the world population. Atopic dermatitis is the most common type and generally starts in childhood. [1] [2] In the United States, it affects about 10–30% of people. [2] Contact dermatitis is twice as common in females as in males. [11]
Dilated blood vessels in the superficial vascular plexus; Mild superficial perivascular infiltrate of lymphocytes, histiocytes and occasional neutrophils. There is some exocytosis of inflammatory cells but not as prominent as in nummular dermatitis; Typical findings: [5] Psoriasiform hyperplasia, initially slight, with mild spongiosis
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Skin biopsies are not indicated for bites or stings, since the histomorphologic appearance is non-specific. Bites and stings as well as other conditions (e.g. drug reactions, urticarial reactions , and early bullous pemphigoid ) can cause microscopic changes such as a wedge -shaped superficial dermal perivascular infiltrate consisting of ...
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