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A phase III study indicated that MDMA-assisted therapy represents a potential breakthrough treatment for severe PTSD that merits expedited clinical evaluation. [17] Based on this study, MDMA-assisted psychotherapy was granted breakthrough therapy designation by the FDA, a designation that indicates that there is preliminary evidence that an intervention might offer a substantial improvement ...
MDMA is also known to decrease fear around memories and increase fear extinction of traumatic memories. [ 8 ] [ 11 ] [ 12 ] [ 13 ] Lastly, MDMA helps reduce the activation of the amygdala (associated with an increase in fear) and increases the activation of the frontal cortex (associated with better processing and control) when retrieving memories.
MDMA-assisted psychotherapy is also currently in Phase 2 trials for eating disorders, [11] anxiety associated with life-threatening illness, [12] and social anxiety in autistic adults. [ 13 ] Psilocybin , a compound in psilocybin mushrooms that serves as a prodrug for psilocin , is currently being investigated in clinical trials of Hallucinogen ...
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(Reuters) -Lykos Therapeutics will lay off 75% of its workforce, or about 100 employees, and founder Rick Doblin will leave the board, the company said on Thursday, days after the U.S. FDA ...
Commonly known as ecstasy or molly, MDMA has long been seen by advocates as a potential treatment for mental health disorders and to have therapeutic applications beyond its illicit use.
Effects of MDMA-assisted psychotherapy can be observed up to 12 months after receiving 2-3 active sessions of moderate to high dose MDMA (75–125 mg). [12] It is important to note that given the difficulties with appropriate blinding in trials of MDMA- and psychedelic-assisted psychotherapy the results are likely overestimated.
MDMA Water intoxication Died from water intoxication secondary to use of MDMA [86] Len Bias: 1963 1986 22 Basketball player Cocaine Accidental [87] Big George: 1957 2011 53 Presenter, broadcaster Mephedrone: Unknown Drug-induced heart attack. [88] Big Moe: 1974 2007 33 Musician Unspecified Unknown Drug-induced heart attack [89] Bam Bam Bigelow ...