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The segmentary bronchi subdivide into fourth order, fifth order and sixth order segmental bronchi before dividing into the bronchioles. The bronchioles are histologically distinct from the bronchi in that their walls do not have hyaline cartilage and they have club cells in their epithelial lining.
Instead of hard cartilage, the bronchi and bronchioles are composed of elastic tissue. The lungs are made up of thirteen different kinds of cells, eleven types of epithelial cell and two types of mesenchymal cell. [13] The epithelial cells form the lining of the tracheal, and bronchial tubes, while the mesenchymal cells line the lungs.
Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells. Cell division is a normal process used by the body for growth and repair. A parent cell divides to form two daughter cells, and these daughter cells are used to build new tissue or to replace cells that have died because of ...
Adenocarcinoma in situ (AIS) of the lung —previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma.It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern.
Another important cell type is the pulmonary neuroendocrine cell. These are innervated cells that only make up around 0.5% of the respiratory epithelial cells. [7] The ciliated cells are columnar epithelial cells with specialized ciliary modifications. The ciliated cells make up between 50 and 80 per cent of the epithelium. [8]
The main or primary bronchi enter the lungs at the hilum and initially branch into secondary bronchi also known as lobar bronchi that supply air to each lobe of the lung. The lobar bronchi branch into tertiary bronchi also known as segmental bronchi and these supply air to the further divisions of the lobes known as bronchopulmonary segments.
A bronchus (/ ˈ b r ɒ ŋ k ə s / BRONG-kəs; pl.: bronchi, / ˈ b r ɒ ŋ k aɪ / BRONG-ky) is a passage or airway in the lower respiratory tract that conducts air into the lungs.The first or primary bronchi to branch from the trachea at the carina are the right main bronchus and the left main bronchus.
In “Type 2” the bronchus is contained in the tumor. These types are more common in malignant nodules. A compressed and narrowed bronchus is defined as “Type 3”, and can occur in both benign and malignant nodules. Narrowing of the proximal bronchial tree is described as “type 4” and is associated with malignancy.