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  2. Pernicious anemia - Wikipedia

    en.wikipedia.org/wiki/Pernicious_anemia

    The Schilling test distinguished PA from other forms of B 12 deficiency, [50] specifically, from Imerslund–Gräsbeck syndrome, a B 12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. [1] Vitamin B12 deficiency is also prevalent in patients having Crohn's disease (CD) so it should be differentiated. [62]

  3. Imerslund–Gräsbeck syndrome - Wikipedia

    en.wikipedia.org/wiki/Imerslund–Gräsbeck_syndrome

    Vitamin B 12 is not found in plant sources; a vegetarian diet can be a risk factor for vitamin B 12 deficiency. Normal daily intake of vitamin B 12 is 7–30 micro gram, cooking has minimal effect on the structure of this vitamin. The minimal daily adult requirement is 1–3 micro gram, and the human body is able to store at any one time about ...

  4. Vitamin B12 deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12_deficiency

    Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [ 2 ] [ 8 ] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.

  5. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Pernicious anemia is the result of inadequate production of the protein intrinsic factor needed by the body to absorb vitamin B 12, causing a reduction of new red blood cells. [8] Vitamin B 12 deficiency anemia due to selective vitamin B 12 malabsorption with proteinuria: Vitamin B 12 deficiency anemia due to selective vitamin B 12 ...

  6. Vitamin B12 Is a Power Nutrient. Here's How to Know If ... - AOL

    www.aol.com/vitamin-b12-power-nutrient-heres...

    Pernicious anemia, or Addison's anemia, is an autoimmune disease which decreases red blood cell count, caused by the body's inability to properly absorb vitamin B12. It can cause diarrhea, pale ...

  7. Vitamin B12 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12

    Vitamin B 12 was discovered as a result of pernicious anemia, an autoimmune disorder in which the blood has a lower than normal number of red blood cells, due to a deficiency of vitamin B 12. [ 5 ] [ 16 ] The ability to absorb the vitamin declines with age, especially in people over 60.

  8. Megaloblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Megaloblastic_anemia

    Vitamin B 12 deficiency is but one among the conditions that can lead to dysfunction of this enzyme and a buildup of its substrate, methylmalonic acid, the elevated level of which can be detected in the urine and blood. Due to the lack of available radioactive Vitamin B 12, the Schilling test is now largely a historical artifact.

  9. Subacute combined degeneration of spinal cord - Wikipedia

    en.wikipedia.org/wiki/Subacute_combined...

    Prolonged deficiency of vitamin B 12 leads to irreversible nervous system damage. HIV-associated vacuolar myelopathy can present with a similar pattern of dorsal column and corticospinal tract demyelination. [citation needed] It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must