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Formal guidance on dilapidations exists such as the PLA protocol which was currently adopted under the Civil Procedure Rules in 2012. [5] The Royal Institution of Chartered Surveyors produces a guidance note on dealing with dilapidations claims and this is currently in its sixth edition. [ 6 ]
A 2024 systematic review of the literature found that chemoradiation with 5-FU and mitomycin C, as used in the Nigro Protocol, improves outcomes like colostomy-free survival in anal cancer patients compared to alternatives like cisplatin. However, it can lead to more severe side effects, especially blood-related toxicity. [7]
The majority of drugs used in cancer chemotherapy are cytostatic, many via cytotoxicity. A fundamental philosophy of medical oncology , including combination chemotherapy, is that different drugs work through different mechanisms, and that the results of using multiple drugs will be synergistic to some extent.
RICS has close links with many national surveying institutions [example needed] and is a founding member association of the International Federation of Surveyors (FIG). Within RICS the primary areas of practice represented at FIG are geomatics (land and hydrographic survey), environment, planning, construction and valuation.
There are a few possible causes of resistance in cancer, one of which is the presence of small pumps on the surface of cancer cells that actively move chemotherapy from inside the cell to the outside. Cancer cells produce high amounts of these pumps, known as p-glycoprotein, in order to protect themselves from chemotherapeutics. Research on p ...
How can you tell if they’re safe past their expiration dates? Here, doctors explain how long most vitamins last and any risks associated with taking expired vitamins.
The RICS was founded in London in 1868 and has more than 120,000 members globally, although less than 10% of RICS members have the specialist (chartered building surveyor) designation. They work closely with professional organisations around the globe. A chartered status is regarded as an enhancement to a building surveyor's professional status.
Escape the Crate offers the experience of an escape room, but delivered to the recipient’s home. Every game is complete with a theme, story, clues, and props, and can take several hours to crack ...