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The initial case in human outbreaks of Nipah virus has always been zoonotic [8] from exposure to contaminated secretions or tissues of infected bats or pigs. Subsequent human-to-human transmission of Nipah virus occurs via close contact with NiV-infected persons or exposure to NiV-infected body fluids (e.g., blood, urine, nasal secretions). [1]
The Nipah virus structural model, constructed at an atomic resolution, depicts a particle with a diameter of 90 nm, adorned with spikes. This model affords a glimpse into the virus's interior. The Nipah virus is known for its high mortality rate and is viewed as a potential candidate for the next pandemic.
Nipah virus (NiV) replication cycle As all mononegaviral genomes, Hendra virus and Nipah virus genomes are non-segmented, single-stranded negative-sense RNA. Both genomes are 18.2 kb in length and contain six genes corresponding to six structural proteins.
Mononegavirales is an order of negative-strand RNA viruses which have nonsegmented genomes. Some members that cause human disease in this order include Ebola virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah virus, and rabies virus.
The virus is spread by bats. For premium support please call: 800-290-4726 more ways to reach us
The virus firstly struck pig-farms in the suburb of Ipoh in Perak with the occurrence of respiratory illness and encephalitis among the pigs, where it was initially believed to have been caused by Japanese encephalitis (JE), due to four serum samples from 28 infected humans in the area which tested positive for JE-specific Immunoglobulin M (IgM) which is also confirmed by the findings of the ...
The virus is often transmitted by bats. For premium support please call: 800-290-4726 more ways to reach us
By Rupam Jain. New Delhi (Reuters) - Experts have fanned out in India's southern state of Kerala to collect samples of fluid from bats and fruit trees in a region where the deadly Nipah virus has ...