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Rift Valley fever (RVF) is a viral disease of humans and livestock that can cause mild to severe symptoms. The mild symptoms may include: fever , muscle pains , and headaches which often last for up to a week.
Butchering livestock transmitted the virus. [1] East Africa had a regional outbreak of Rift Valley fever in late 2006 that affected Kenya, Somalia, and Tanzania. During outbreak, 1062 people were infected with Rift Valley fever and 394 people died between December 2006 and December 2007. [2]
Rift Valley fever (RVF) outbreaks affecting humans and livestock occur across sub-Saharan Africa, with outbreaks occurring elsewhere infrequently.Outbreaks usually correspond with the El Niño, associated with increased rainfall and flooding, causing increases in the mosquito population, which act as vector for the virus. [1]
DIC is thought to cause bleeding in Rift Valley, Marburg, and Ebola fevers. For filoviral hemorrhagic fevers, there are four general mechanisms of pathogenesis. The first mechanism is dissemination of virus due to suppressed responses by macrophages and dendritic cell (antigen presenting cells).
Prevention of viral hemorrhagic fever is similar for the different viruses. There are a number of different viral hemorrhagic fevers including Ebola virus disease , Lassa fever , Rift valley fever , Marburg virus disease , Crimean-Congo haemorrhagic fever (CCHF) and yellow fever . [ 1 ]
1956: Cache Valley virus isolated in Culiseta inornata mosquitoes in Utah 1960: La Crosse virus was first recognized in a fatal case of encephalitis in La Crosse, Wisconsin. 1977: Rift Valley Fever virus caused approximately 200,000 cases and 598 deaths in Egypt. 2017: Bunyavirales order is created
Arbovirus is an informal name for any virus that is transmitted by arthropod vectors.The term arbovirus is a portmanteau word (arthropod-borne virus). [1] Tibovirus (tick-borne virus) is sometimes used to more specifically describe viruses transmitted by ticks, a superorder within the arthropods. [2]
Additionally, the fusion of Rift Valley fever virus (RVFV) in late endosomes is inhibited by the interferon-induced transmembrane proteins 2 and 3 (IFITIM2 and IFITIM3). Third, the viral and endosomal membranes are fused to allow for the release of the viral ribonucleoprotein complexes into the cytoplasm (Also the site of viral transcription ...