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Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
The principles of treatment for MDR-TB and for XDR-TB are the same. Second-line drugs are more toxic than the standard anti-TB regimen and can cause a range of serious side-effects including hepatitis, depression, hallucinations, and deafness. [14] Patients are often hospitalized for long periods, in isolation.
Bedaquiline, sold under the brand name Sirturo, is a medication used for the treatment of active tuberculosis. [1] Specifically, it is used to treat multi-drug-resistant tuberculosis along with other medications for tuberculosis. [1] [8] [9] It is taken by mouth. [3] Common side effects include nausea, joint pains, headaches, and chest pain. [1]
Common side effects include headache, dizziness, and nausea. [3] Other side effects include QT prolongation. [2] Use in pregnancy has not been extensively studied, but there have been reports of success [9] and it is currently recommended as part of the standard treatment regimen for pregnant women with rifampicin-resistant tuberculosis in South Africa.
Pyrazinamide is used in the first 2 months of treatment to reduce the duration of treatment required. [7] Regimens not containing pyrazinamide must be taken for 9 months or more. Pyrazinamide is a potent antiuricosuric drug [8] and consequently has an off-label use in the diagnosis of causes of hypouricemia and hyperuricosuria. [9] It acts on ...
There is some efficacy for linezolid to treat those with XDR-TB but side effects and discontinuation of medications were common. [160] [161] Bedaquiline is tentatively supported for use in multiple drug-resistant TB. [162] XDR-TB is a term sometimes used to define extensively resistant TB, and constitutes one in ten cases of MDR-TB. Cases of ...
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Specifically it is a second line treatment used for active drug resistant tuberculosis. [1] It is given by injection into a vein or muscle. [1] Common side effects include kidney problems, hearing problems, poor balance, and pain at the site of injection. [1] Other side effects include paralysis resulting in the inability to breathe. [1]