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Inside of a bone showing the trabecular structure A typical carcinoid tumor of the lung showing a trabecular pattern of elongated groups of cells.. A trabecula (pl.: trabeculae, from Latin for 'small beam') is a small, often microscopic, tissue element in the form of a small beam, strut or rod that supports or anchors a framework of parts within a body or organ.
The corduroy sign reflects the characteristic trabecular changes caused by the hemangioma, namely, thinning of trabeculae as well as thickened vertical struts, resulting from compensatory hypertrophy of the remaining trabeculae to maintain structural integrity. These vertical trabecular striations give rise to the "corduroy" appearance on imaging.
These areas rely on the trabecular bone for strength, so the intense remodeling causes these areas to degenerate most when the remodeling is imbalanced. [citation needed] Around the ages of 30–35, cancellous or trabecular bone loss begins. Women may lose as much as 50%, while men lose about 30%. [38]
Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. [1] [2] It can manifest in localized or generalized osteosclerosis.
The trabecular bone score is a measure of bone texture correlated with bone microarchitecture and a marker for the risk of osteoporosis. Introduced in 2008, [ 1 ] its main projected use is alongside measures of bone density in better predicting fracture risk in people with metabolic bone problems.
Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones. The affected bones show signs of dysregulated bone remodeling at the microscopic level, specifically excessive bone breakdown and subsequent disorganized new bone ...
The trabecular bone is first resorbed by osteoclasts, creating a shallow resorption pit known as a "Howship's lacuna". Then osteoblasts deposit compact bone within the resorption pit. Eventually, the fracture callus is remodelled into a new shape which closely duplicates the bone's original shape and strength.
Overt hyperthyroidism caused by Grave's Disease is associated with accelerated bone remodeling (resulting in increased porosity of cortical bone and reduced volume of trabecular bone). This can lead to reduced bone density and eventually osteoporosis as well as increased fracture rates. The increased hip fracture rates later in life in turn ...