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It may help with incontinence, urinary frequency, and urinary urgency. [3] Benefits appear similar to other antimuscarinics such as oxybutynin, tolterodine, and darifenacin. [4] It is also used to treat neurogenic detrusor overactivity (NDO), a form of bladder dysfunction related to neurological impairment, in children ages two years and older. [2]
An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, [1] opposing diuresis. [2] Its effects are opposite that of a diuretic . The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin .
Urinary retention is an inability to completely empty the bladder. [1] Onset can be sudden or gradual. [1] When of sudden onset, symptoms include an inability to urinate and lower abdominal pain. [1] When of gradual onset, symptoms may include loss of bladder control, mild lower abdominal pain, and a weak urine stream. [1]
Extended-release formulations decrease the number of weekly incontinence episodes by an average of 90% compared to an untreated state. [11] Some studies have identified advantages of transdermal oxybutynin over capsules, finding decreased frequency of incontinence episodes and increased average voided volume of urine. [12]
Excessive urination that’s not due to copious water or beverage consumption can have multiple causes, including overactive bladder syndrome, diabetes, a urinary tract infection or medications ...
Frequent urination is due to the increased loss of water that has not been retained from the body as a result of a concomitant relationship with sodium loss from the convoluted tubule. The short-term anti-hypertensive action is based on the fact that thiazides decrease preload, decreasing blood pressure.
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