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Since peripheral anaesthesia of the injured sciatic nerve after the development of pain-related behaviours was also found to attenuate thermal hyperalgesia in CCI rats, dextrorphan or ketamine treatment, alone or in combination with local nerve anaesthesia, may prove to be a useful therapeutic means for clinical management of neuropathic pain ...
In people with diabetic peripheral neuropathy, two reviews make a case for nerve decompression surgery as an effective means of pain relief and support claims for protection from foot ulceration. [ 114 ] [ 115 ] There is less evidence for efficacy of surgery for non-diabetic peripheral neuropathy of the legs and feet.
Treatment Occupational therapy, weight decrease (management) [ 1 ] Polyneuropathy (from Greek poly- 'many' neuro- 'nerve' and -pathy 'sickness') is damage or disease affecting peripheral nerves ( peripheral neuropathy ) in roughly the same areas on both sides of the body, featuring weakness , numbness , and burning pain. [ 1 ]
Nerve decompressions are associated with a significant reduction in pain, in some cases the complete elimination of pain. [ 64 ] [ 58 ] [ 59 ] For patients with diabetic peripehral neuropathy (which affects 30% of diabetes patients [ 65 ] ) and superimposed nerve compression, this may be treatable with multiple nerve decompressions.
Rapid treatment is a critical component of care in patients affected with leprosy, delayed care results in permanent loss of sensation and tissue damage which requires an extensive treatment regime. [16] Lyme disease, caused by the spirochete Borrelia burgdorferi, is a tick-borne illness with both peripheral and central neurological manifestations.
Small fiber peripheral neuropathy is a type of peripheral neuropathy that occurs from damage to the small unmyelinated and myelinated peripheral nerve fibers. These fibers, categorized as C fibers and small Aδ fibers, are present in skin, peripheral nerves, and organs. [1]
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