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2. List of 5α-reductase inhibitors - Wikipedia

   en.wikipedia.org/wiki/List_of_5α-reductase...

   This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

3. DHT Blockers for Hair Loss: 4 Things to Know - AOL

   www.aol.com/dht-blockers-hair-loss-4-115800682.html

   Researchers believe that men affected by androgenetic alopecia tend to have higher levels of the 5-alpha-reductase enzyme, which converts testosterone into DHT, as well as an increased level of ...

4. How Effective Is Saw Palmetto as a Hair Loss Treatment? - AOL

   www.aol.com/effective-saw-palmetto-hair-loss...

   A 2009 review found that saw palmetto is the most popular botanically derived 5 alpha reductase (5aR) inhibitor. Another meta-analysis looked at both oral and topical saw palmetto.

5. 5α-Reductase inhibitor - Wikipedia

   en.wikipedia.org/wiki/5α-reductase_inhibitor

   Thus, inhibition results in decreased amounts of DHT. Because of this, slight elevations in testosterone and estradiol levels occur. [36] The 5α-reductase reaction is a rate-limiting step in the testosterone reduction and involves the binding of NADPH to the enzyme followed by the substrate. [4] [37] Substrate + NADPH + H + → 5α-substrate ...

6. Management of hair loss - Wikipedia

   en.wikipedia.org/wiki/Management_of_hair_loss

   They catalyse formation of the androgens testosterone and DHT, which in turn regulate hair growth. Androgens have different effects at different follicles: they stimulate IGF-1 at facial hair, causing hair regrowth, but stimulate TGF β1, TGF β2, dickkopf1 and IL-6 at the scalp, causing hair follicle miniaturisation. [80]

7. 6 Best Men's Shampoos for Hair Growth - AOL

   www.aol.com/lifestyle/6-best-mens-shampoos-hair...

   One review of seven studies found that oral and topical supplements containing saw palmetto improved hair quality by 60 percent, increased hair density by 83 percent and raised total hair count by ...