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Powered by ATP, the pump moves sodium and potassium ions in opposite directions, each against its concentration gradient. In a single cycle of the pump, three sodium ions are extruded from and two potassium ions are imported into the cell. Active transport is the movement of a substance across a membrane against its concentration gradient. This ...
Two variations of the Na-K-2Cl symporter exist and are known as NKCC1 and NKCC2. The NKCC1 cotransport protein is found throughout the body but NKCC2 is found only in the kidney and removes the sodium, potassium, and chloride found in the body's urine, so it can be absorbed into the blood. [17]
Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins . It is required by animals, which use it as a cofactor in DNA synthesis , and in both fatty acid and amino acid metabolism . [ 3 ]
[citation needed] Primary active transport uses adenosine triphosphate (ATP) to move specific molecules and solutes against its concentration gradient. Examples of molecules that follow this process are potassium K +, sodium Na +, and calcium Ca 2+. A place in the human body where this occurs is in the intestines with the uptake of glucose.
This process is in contrast to passive transport, which allows molecules or ions to move down their concentration gradient, from an area of high concentration to an area of low concentration, without energy. Active transport is essential for various physiological processes, such as nutrient uptake, hormone secretion, and nerve impulse transmission.
The enzyme hydrogen potassium ATPase (H + /K + ATPase) is unique to the parietal cells and transports the H + against a concentration gradient of about 3 million to 1, [citation needed] which is the steepest [citation needed] ion gradient formed in the human body.
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