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Peripheral artery disease (PAD) is a vascular disorder that causes abnormal narrowing of arteries other than those that supply the heart or brain. [ 5 ] [ 15 ] PAD can happen in any blood vessel, but it is more common in the legs than the arms.
Peripheral arterial disease is a blockage in the arteries that carry blood away from your heart. It usually develops in your legs. ... The most common cause is coronary artery disease.
Peripheral Artery Disease Peripheral artery disease is a narrowing of one of the arteries that carries blood to your limbs. It most commonly affects your legs.
Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. [3] This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, [3] and poor sleep, [7] [8] among other things.
Macroangiopathy may cause other complications, such as ischemic heart disease, stroke and peripheral vascular disease which contributes to the diabetic foot ulcers and the risk of amputation. In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed , leak protein , and slow the flow of blood through ...
High levels of LDL, cholesterol, or triglycerides can cause peripheral artery disease, in which the arteries that carry blood to your legs can narrow or become blocked. You might notice pain or ...
In treating renal artery disease, a 2014 study indicates that balloon angioplasty can improve diastolic blood pressure and potentially reduce antihypertensive drug requirements. [30] In the case of peripheral artery disease, treatment to prevent complications is important; without treatment, sores or gangrene (tissue death) may occur. [citation ...
When atherosclerosis has become severe and caused irreversible ischemia, such as tissue loss in the case of peripheral artery disease, surgery may be indicated. Vascular bypass surgery can re-establish flow around the diseased segment of the artery, and angioplasty with or without stenting can reopen narrowed arteries and improve blood flow.
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