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Signs and symptoms of mild cinchonism (which may occur from standard therapeutic doses of quinine) include flushed and sweaty skin, ringing of the ears (), blurred vision, impaired hearing, confusion, reversible high-frequency hearing loss, headache, abdominal pain, rashes, drug-induced lichenoid reaction (lichenoid photosensitivity), [1] vertigo, dizziness, nausea, vomiting and diarrhea.
Many different medications can cause diarrhea. Antibiotics are one type. “Antibiotics may upset the delicate balance of intestinal flora and lead to diarrhea in certain people,” Dr. Ahmad says.
The condition is usually caused by Gram-positive enteric commensal bacteria of the gut (). Clostridioides difficile is a species of Gram-positive bacteria that commonly causes severe diarrhea and other intestinal diseases when competing bacteria are wiped out by antibiotics, causing pseudomembranous colitis, whereas Clostridium septicum is responsible for most cases of neutropenic enterocolitis.
There are many causes of infectious diarrhea, which include viruses, bacteria and parasites. [29] Infectious diarrhea is frequently referred to as gastroenteritis. [30] Norovirus is the most common cause of viral diarrhea in adults, [31] but rotavirus is the most common cause in children under five years old. [32]
Federal health officials are investigating overdoses and deaths involving the use of anti-diarrhea drugs.
As with other opiates, chronic use of codeine can cause physical dependence which can lead to severe withdrawal symptoms if a person suddenly stops the medication. Withdrawal symptoms include drug craving, runny nose, yawning, sweating, insomnia, weakness, stomach cramps, nausea, vomiting, diarrhea, muscle spasms, chills, irritability, and pain.
Partial agonists, like the anti-diarrhea drug loperamide and antagonists, like naloxegol for opioid-induced constipation, do not cross the blood–brain barrier, but can displace other opioids from binding to those receptors in the myenteric plexus. Because opioids are addictive and may result in fatal overdose, most are controlled substances.
Chronic conditions, such as irritable bowel syndrome or Crohn's disease, can cause severe diarrhea lasting for weeks or months. Diseases, drugs, and indigestible dietary fats that interfere with the intestineal absorption may cause steatorrhea (oily rectal discharge & fatty diarrhea) and
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