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Telmisartan, sold under the brand name Micardis among others, is a medication used to treat high blood pressure and heart failure. [ 3 ] [ 6 ] It is a reasonable initial treatment for high blood pressure. [ 6 ]
Valsartan, telmisartan and EXP 3174 have similar affinities that are about ten-fold less than that of candesartan. Losartan has the least affinity. [6] ARBs' affinity for the AT 2 receptor is generally much lower (or around 10,000 times less) than for the AT 1 subtype. Therefore, they allow unhindered stimulation of the AT 2 receptor. [20]
Telmisartan works by blocking the effects of angiotensin II while hydrochlorothiazide works by decreasing the kidneys' ability to retain water. [2] The combination was approved for medical use in the United States in November 2000, [6] [7] and in the European Union in April 2002.
Telmisartan has a PPARg-agonist- activity It says so at Opie, 8th edition, 2013, p171. I am not sure if we should state it at the article as it is mentioned in a secondary sentence... I feel the PPARg-agonist activity is really low. Same page says that telmisartan "reduced new-onset electrocardiographic LVH by 37%".
A flight attendant has reportedly been injured after falling from a plane at an airport in England. On Monday, Dec. 16, at approximately 4:30 p.m. local time, the woman — who works for the ...
She then noted recent reporting by the Wall Street Journal that detailed how White House aides covered up Biden’s mental decline over the past four years.. The explosive report says staffers ...
The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release.
Some troops leave the battlefield injured. Others return from war with mental wounds. Yet many of the 2 million Iraq and Afghanistan veterans suffer from a condition the Defense Department refuses to acknowledge: Moral injury.
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