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Ototoxicity is defined as the toxic effect on the functioning of the inner ear, which may lead to temporary or permanent hearing loss (cochleotoxic) and balancing problems (vestibulotoxic). [1] Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear
Otomycosis does not usually cause as much canal skin edema as does acute bacterial external otitis. While a severe pressure type of pain is a prominent feature of advanced cases, the ear is usually much less tender, if at all, to traction or tragal pressure.
At high doses, quinine, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug. [20] Erectile dysfunction medications may have the potential to cause hearing loss. [36] However the link between erectile dysfunction medications and hearing loss remains ...
Fungal ear canal infections, also known as otomycosis, range from inconsequential to extremely severe. Fungi can be saprophytic, in which there are no symptoms and the fungus simply co-exists in the ear canal in a commensal relationship with the host, in which case the only physical finding is the presence of a fungus. If the fungus begins ...
AIED is generally caused by either antibodies or immune cells that cause damage to the inner ear. There are several theories that propose a cause of AIED: Bystander damage – Physical damage to the inner ear may lead to cytokine release that signals for an immune response. This may be a component of the "attack/remission cycle" of AIED. [9]
Otitis media, or middle ear infection, involves the middle ear. In otitis media, the ear is infected or clogged with fluid behind the ear drum, in the normally air-filled middle-ear space. This is the most common infection and very common in babies younger than 6 months.
A diagnosis usually can be made by the presenting signs and symptoms alone. If the diagnosis is unclear, a throat swab or stool specimen may be taken. Medications are usually not needed as hand, foot, and mouth disease is a viral disease that typically resolves on its own. Under research [15] [16] Sin Nombre virus: Hantavirus Pulmonary Syndrome ...
The link between NSAIDs and hearing loss tends to be greater in women, especially those who take ibuprofen six or more times a week. [36] Others may cause permanent hearing loss. [37] The most important group is the aminoglycosides (main member gentamicin) and platinum based chemotherapeutics such as cisplatin and carboplatin. [38] [39]
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