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Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands.
Normal arterial blood oxygen saturation levels in humans are 96–100 percent. [1] If the level is below 90 percent, it is considered low and called hypoxemia . [ 2 ] Arterial blood oxygen levels below 80 percent may compromise organ function, such as the brain and heart, and should be promptly addressed.
Tissue hypoxia from low oxygen delivery may be due to low haemoglobin concentration (anaemic hypoxia), low cardiac output (stagnant hypoxia) or low haemoglobin saturation (hypoxic hypoxia). [79] The consequence of oxygen deprivation in tissues is a switch to anaerobic metabolism at the cellular level.
People with low oxygen levels will often require supplemental oxygen to increase their oxygen saturation. “We know that some people are still kind of avoidant of health care because they are ...
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A low PaO 2 indicates abnormal oxygenation of blood and a person is known as having hypoxemia. (Note that a low PaO 2 is not required for the person to have hypoxia as in cases of Ischemia, a lack of oxygen in tissues or organs as opposed to arterial blood.) At a P a O 2 of less than 60 mm Hg, supplemental oxygen should be administered.
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