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Her research program revealed a genetic variation in the human catechol-O-methyltransferase gene with pain sensitivity and the risk of chronic pain conditions (Hum. Mol. Genet., 2004; Science, 2006), individual differences in responses to analgesic drugs being driven by genetics (Hum. Mol. Genet., 2009; Pain, 2020), and the protective role of ...
Ensembl makes these data freely accessible to the world research community. All the data and code produced by the Ensembl project is available to download, [7] and there is also a publicly accessible database server allowing remote access. In addition, the Ensembl website provides computer-generated visual displays of much of the data.
It has also improved the speed and sophistication of the search engine, and expanded from a gene-centric dogma to contain gene-set analyses. Version 3 of the database gathers information from more than 90 database resources based on a consolidated gene list. It has also added a suite of GeneCards tools which focus on more specific purposes.
NCBI provides the Gene database, Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), dbSNP (a database of single-nucleotide polymorphisms), the Reference Sequence Collection, a map of the human genome, and a taxonomy browser, and coordinates with the National Cancer Institute to provide the Cancer ...
fMRI coordinate database Human Macroscopic Descriptive Healthy Yes [10] BrainMaps: Atlas, high resolution stained sections from brains Human, primate and non-primate (14 species in all) Neuron and Macroscopic Images Healthy No [11] Brain/MINDS Dataportal: Atlas, in-vivo and ex-vivo MRI scans, ECoG recordings Common Marmoset, Human Macroscopic ...
ClinVar is a public archive with free access to reports on the relationships between human variations and phenotypes, with supporting evidence.The database includes germline and somatic variants of any size, type or genomic location.
dbSNP is an online resource implemented to aid biology researchers. Its goal is to act as a single database that contains all identified genetic variation, which can be used to investigate a wide variety of genetically based natural phenomena.
Several projects to improve RefSeq services are currently in development by the NCBI, often in collaboration with research centers such as EMBL-EBI: . Consensus CDS (CCDS): This project aims to identify a core set of human and mouse protein-coding regions and standardize sets of genes with high and consistent levels of genomic annotation quality.